How to Make a Vaccine

Rhodes John
"In this book, [the author] aims to combine his lifetime's experience in both academic and industrial spheres, his passionate interest in the history of immunology and vaccination, and his proven ability to explain the underlying science to uninitiated readers. This is a short book that takes a long view. The principles of vaccination have remained the same from the start of the vaccine story, and some strong contenders in today's race for a COVID-19 vaccine have stepped straight out of history in a re-invented form, and are just as likely to succeed as the latest gene-based candidates (the subject of Rhodes's own work on vaccines). While providing this historical backdrop, Rhodes explains the fundamentals of the science, revealing the unifying principles shaping the race and the intriguing details of vaccine discovery--an area beyond the reach of magazine and newspaper articles. This is, Rhodes says, what drives and motivates all vaccine researchers, and it is this intellectual excitement that he wants now to share with general readers"--




Distinguished expert in vaccine development John Rhodes tells the story of the first approved COVID-19 vaccines and offers an essential, up-to-the-minute primer on how scientists discover, test, and distribute vaccines.

As the COVID-19 pandemic has affected every corner of the world, changing our relationship to our communities, to our jobs, and to each other, the most pressing question has been--when will it end? Researchers around the globe are urgently trying to answer this question by racing to test and distribute a vaccine that could end the greatest public health threat of our time. In How to Make a Vaccine, an expert who has firsthand experience developing vaccines tells an optimistic story of how three hundred years of vaccine discovery and a century and a half of immunology research have come together at this powerful moment--and will lead to multiple COVID-19 vaccines.

Dr. John Rhodes draws on his experience as an immunologist, including working alongside a young Anthony Fauci, to unravel the mystery of how vaccines are designed, tested, and produced at scale for global deployment. Concise and accessible, this book describes in everyday language how the immune system evolved to combat infection, how viruses responded by evolving ways to evade our defenses, and how vaccines do their work. That history, and the pace of current research developments, make Rhodes hopeful that multiple vaccines will protect us. Today the complex workings of the immune system are well understood. The tools needed by biomedical scientists stand ready to be used, and more than 160 vaccine candidates have already been produced. But defeating COVID-19 won't be the end of the story: Rhodes describes how discoveries today are also empowering scientists to combat future threats to global health, including a recent breakthrough in the development of genetic vaccines, which have never before been used in humans.

As the world prepares for a vaccine, Rhodes offers a current and informative look at the science and strategies that deliver solutions to the crisis.

More Information
Publisher University of Chicago Press
ISBN-10 022679251X
ISBN-13 9780226792514
GTIN-13 9780226792514
GTIN-14 09780226792514
Subtitle An Essential Guide for Covid-19 and Beyond
Author Rhodes John
Edition 1
Language Code eng
Page Count 184
Publication Date Apr 11, 2021
Dimension 5.5 in 8.4 in 0.7 in